What attackers do. Attackers use valid accounts to log into services that accept remote connections, such as remote desktop, SSH, SMB administrative shares, VNC or remote management, and move between systems. This serves the Lateral Movement tactic.
How to defend. Restrict remote access services to the hosts and users that need them, using firewalls and jump hosts. Require MFA for remote administration, disable unneeded services and use separate admin accounts. Collect authentication logs from endpoints and servers centrally. Use local administrator password randomisation so one compromised local password cannot open every host.
Signs to look for. Look for remote logins between workstations, admin accounts logging into many hosts quickly, connections from unusual sources and remote sessions outside working hours. A common gap is not collecting authentication logs from workstations.