What attackers do. Attackers route traffic through intermediary systems, such as compromised hosts, rented servers, residential proxy networks or anonymising services, to hide where it really comes from or to reach systems that are not directly reachable. This serves the Command and Control tactic.
How to defend. Restrict outbound connections to known proxies and block anonymising networks where business allows. Inside the network, monitor for hosts acting as relays between segments. On the identity side, use reputation data on residential proxies and anonymisers when evaluating logins.
Signs to look for. Look for internal hosts listening on unusual ports and forwarding traffic, connections to known proxy or anonymisation infrastructure, and logins whose source changes rapidly between unrelated networks. A common gap is that residential proxies make malicious logins appear to come from ordinary home connections.